Synthesis Medical is committed to optimising healthcare delivery for long-term conditions


Synthesis Medical Managing Director, Paul Mitchell, has published extensively on systematic approaches to fragility
fracture care and prevention. Paul’s publications, including peer-reviewed journal articles, reports and widely
disseminated practical guides, are listed below. Details of Paul’s presentations at conferences throughout the world
are also available from

1. Mitchell PJ. Secondary prevention and estimation of fracture risk. Best Practice and Research Clinical Rheumatology.
2013 Dec;27(6):789-803. Link

2. Mitchell PJ and Lee DB. Systematic approaches to fragility fracture prevention. Osteologie 2014; 23:39-44. Link

3. Mitchell PJ. Fracture liaison services in the United Kingdom. Current Osteoporosis Reports. 2013 Dec;11(4):377-84. Link

4. Thériault D, Mitchell PJ and the Osteoporosis Canada FLS Working Group. Make the FIRST break the LAST with
Fracture Liaison Services. Osteoporosis Canada. 2013. Link

5. Åkesson K, Marsh D, Mitchell PJ et al. Capture the Fracture: a Best Practice Framework and global campaign to
break the fragility fracture cycle. Osteoporos International. 2013 Aug;24(8):2135-2152. Link

6. Cornish J, Milsom S, Mitchell PJ et al. Does insufficient access to dual-energy X-ray absorptiometry (DXA) stifle
the provision of quality osteoporosis care in New Zealand? Archives of Osteoporosis. 2013 Dec;8(1-2):120. Link

7. Mitchell PJ. Best Practices in Secondary Fracture Prevention: Fracture Liaison Services. Current Osteoporos Reports.
2013 Mar;11(1):52-60. Link

8. Mitchell PJ. All Wales Audit of Secondary Prevention of Osteoporotic Fractures 2012. All Wales Osteoporosis
Advisory Group (WOAG). 2012. Link

9. Åkesson K and Mitchell P. International Osteoporosis Foundation World Osteoporosis Day Report 2012. Capture
the Fracture: A global campaign to break the fragility fracture cycle. International Osteoporosis Foundation. 2012. Link

10. Mitchell PJ, Spellacy E, Cornish J et al. Bone Care 2020: A systematic approach to hip fracture care and prevention
for New Zealand. Osteoporosis New Zealand. 2012. Link

11. Mitchell PJ and Jordan J. Fracture Liaison Services Resource Pack (Australia). Novartis. 2012.

12. Mitchell PJ. Fracture Liaison Services Resource Pack (New Zealand). Novartis. 2012.

13. Eisman JA, Bogoch ER, Mitchell PJ et al. Making the first fracture the last fracture: ASBMR task force report on
secondary fracture prevention. Journal of Bone and Mineral Research. 2012 Oct;27(10):2039-2046. Link

14. Mitchell PJ and Bateman K. Dementia, falls and fractures: Integrated approaches to improve quality and reduce costs.
Novartis. 2012.

15. Siris ES, Boonen S, Mitchell PJ et al. What's in a name? What constitutes the clinical diagnosis of osteoporosis?
Osteoporosis International. 2012 Aug;23(8):2093-2097. Link

16. Ebeling P, Davenport G, Evans S, Mitchell P. Osteoporosis challenges. Australian Family Physician. 2012 Apr;41(4):169.

17. Mitchell PJ. Fracture Liaison Services: the UK experience. Osteoporosis International. 2011 Aug;22 Suppl 3:487-494.

18. Cooper C, Mitchell P, Kanis JA. Breaking the fragility fracture cycle. Osteoporosis International. 2011 Jul;22(7):
2049-2050. Link

19. Marsh D, Åkesson K, Mitchell PJ et al. Coordinator-based systems for secondary prevention in fragility fracture
patients. Osteoporosis International. 2011 Jul;22(7):2051-2065. Link

20. Mitchell PJ, Dolan L, Sahota O et al. The Breaking Point Report. The Patients Association, British Menopause Society,
Women’s Health Concern, International Longevity Centre, Amgen and GlaxoSmithKline. 2010.

21. Davie M, Adekunle F, Mitchell P et al. Peripatetic intravenous service for metabolic bone disease: case study in
patient centred-care for new NHS. Current Medical Research and Opinion. 2010 Aug;26(8):2033-2039. Link

22. Goldhahn J, Little D, Mitchell PJ et al. Evidence for anti-osteoporosis therapy in acute fracture situations -
Recommendations of a multidisciplinary workshop of the International Society for Fracture Repair. Bone 2010;46(2):
267-271. Link

23. Mitchell PJ and Adekunle O. Fracture Liaison Service Resource Pack (UK). Novartis. 2010.

24. Mitchell PJ and Harries N. Fracture prevention services: An economic evaluation. Department of Health. 2009. Link

25. Mitchell PJ. All Wales Audit of Secondary Prevention of Osteoporotic Fractures 2009. All Wales Osteoporosis
Advisory Group (WOAG). 2009. Link

26. Martin FC, Harries N, Mitchell PJ et al. Falls and fractures: Effective interventions in health and social care.
Department of Health. 2009. Link

27. Cooper A, McLellan AR, Mitchell PJ et al. Protecting fragile bones: A strategy to reduce the impact of osteoporosis
and fragility fractures in the UK. National Osteoporosis Society. 2009. Link

28. Mitchell PJ. Fracture Liaison Services: a systematic approach to secondary fracture prevention. Osteoporosis
Review 2009;17(1):14-16. Reprint requests to

29. Bayly JR, Francis RM, Mitchell PJ. Changing clinical practice in fracture prevention: a team approach. Geriatric
Medicine 2009;March:S01-S12.

30. Marsh DR, Currie C, Mitchell PJ et al. The care of patients with fragility fracture. BOA-BGS Blue Book 2nd Edition.
British Orthopaedic Association. 2007. Link

31. Gallacher SJ, Gallagher AP, Mitchell PJ et al. The prevalence of vertebral fracture amongst patients presenting
with non-vertebral fractures. Osteoporosis International 2007;18:185-192. Link

32. Dixon T, Mitchell PJ, Beringer T et al. An overview of the prevalence of 25-hydroxy-vitamin-D inadequacy amongst
elderly patients with or without fragility fracture in the United Kingdom. Current Medical Research and Opinion
2006;22(2):405-415. Link